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We envision a future where medicine is humane, precise, personalized and affordable.

Our mission is to serve humankind through scientific research and teaching.

Our research goal is to understand how gene networks control cell behavior. We focus on important cancer genes

and trisomy 21.

We are a research-teaching team. We teach in the classroom, in the lab and on social media.


The Espinosa lab moves to the

UC Denver School of Medicine

September 1, 2015


Exciting times for the Espinosa lab! Joaquín has accepted a new position as Associate Director for Science at the Linda Crnic Institute for Down Syndrome at the University of Colorado Denver School of Medicine (UCD-SOM) in the Anschutz Medical Campus. Consequently, the lab has moved from Boulder to the Department of Pharmacology at UCD-SOM in Aurora. Team members Kelly Sullivan, Matthew Galbraith and Zdenek Andrysik have been appointed as Research Instructors at UCD-SOM. The lab will continue with all its current lines of research and expand its research program in Down Syndrome. We are very excited to be newly immersed in the vibrant environment of the UCD-SOM and the Department of Pharmacology, close to many of our current collaborators. The Functional Genomics Facility has also moved into a space adjacent to the Espinosa lab. Joaquín will retain a partial appointment in the department of Molecular, Cellular and Developmental Biology at CU-Boulder. Click 'Read More' for the press release from the Global Down Syndrome Foundation.

Post-doctoral fellows Anna Guarnieri and Chris Abraham have secured fellowships from the National Institutes of Health and American Cancer Society, respectively. Congratulations!

Dr. Kelly Sullivan publishes in Cell Cycle collabrative work demosntrating a conserved role for the ACAP2 gene in apoptosis. Check the article here

In a follow up study of his 2012 seminal paper in Nature Chemical Biology, post-doc Kelly Sullivan defined the mechanism by which ATM prevents cell death during non-genotoxic activation of p53. Read the paper here

Anna and Chris secure post-doctoral fellowships

Kelly publishes paper in collaboration with the Xue lab.

Kelly publishes paper describing novel role for ATM in the p53 pathway



There is no science without fancy and no art without facts.

-Vladimir Nabokov