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We envision a future where medicine is humane, precise, personalized and affordable.

Our mission is to serve humankind through scientific research and teaching.

Our research goal is to understand how gene networks control cell behavior. We focus on important cancer genes

and trisomy 21.

We are a research-teaching team. We teach in the classroom, in the lab and on social media.


Cell Reports paper on TIP60 and HIF1A makes it to the cover of the Denver Post

July 29, 2016


Our recent paper in Cell Reports describing the interplay between HIF1A and its two co-factors, TIP60 and CDK8, during the cellular response to hypoxia was recently featured in the cover of the Denver Post. Journalist Kevin Simpson summarized the findings in the paper and also described the multiple collaborations that enabled this set of discoveries.

On the origins of long non-coding RNAs: missing link found! Read it here.

Collaborative work with the Taatjes lab at CU-Boulder is published in MCB, reporting a kinase-independent role for CDK19 in the p53 program. Read it here.

A genetic screen leads to identitication of genetic liabilities and pharmacological strategies for MLL-rearranged leukemias. Read the paper here.

Joaquin's piece on lncRNAs is published in TIGS

Collaboration paper on CDK19 comes out in MCB

Paper in collaboration with the Shilatifard lab is published in Cell!



There is no science without fancy and no art without facts.

-Vladimir Nabokov

Awesome post-doctoral fellows wanted!






The Espinosa lab is looking for capable and motivated post-doctoral researchers interested in partaking in one of the many exciting projects in the lab. Apply at: